IMAdult & adolescent ≥16 yr 1 mL. 3-doses standard primary course of vaccination: 1st is administered at the elected date, then 2nd is 1 mth later & 3rd is 6 mth after the 1st dose. A schedule of 3 inj may be given at 0, 7 & 21 days & a 4th dose given 12 mth after the 1st dose in exceptional circumstances. Booster dose May be administered a booster dose of either of the monovalent hepatitis A or B vaccines.
Hypersensitivity to inactivated hepatitis A & rDNA hepatitis B vaccine, or subjects showing signs of hypersensitivity after previous administration of Twinrix Adult or the monovalent hepatitis A or hepatitis B vaccines.
Postpone vaccination in patients w/ acute severe febrile illness. Syncope & rare anaphylactic reaction may occur. Not recommended for postexposure prophylaxis (eg, needle stick injury). Consider additional doses in patients w/ impaired immunity, on hemodialysis & w/ an impaired immune system. Administer SC to patients w/ thrombocytopenia or bleeding disorders. Do not administer IV. Pregnancy & lactation.
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